Sildenafil 25 mg film-coated tablets Sildenafil 50 mg film-coated tablets Sildenafil mg film-coated tablets 2. Qualitative and quantitative composition Each tablet contains 25 mg, 50 mg or mg of sildenafil as citrate Excipient with known effect : Lactose monohydrate 1 mg per 25 mg tablet 2 mg per 50 mg tablet 4 mg per mg tablet. For the full list of excipients, see section 6. Clinical particulars 4. In order for Sildenafil to be effective, sexual stimulation is required. Use in adults The recommended dose is 50 mg taken as needed approximately one hour before sexual activity. Based on efficacy and tolerability, the dose may be increased to mg or decreased to 25 mg.

VIAGRA sildenafil citrate, an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate cGMP -specific phosphodiesterase type 5 PDE5. Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3. The maximum recommended dosing frequency is once per day. VIAGRA is supplied as blue, film-coated, rounded-diamond-shaped tablets containing sildenafil citrate equivalent to 25 mg, 50 mg, or mg of sildenafil. Revised: Sep Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

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Verhamme, in Side Effects of Drugs Annual, Sildenafil has been associated with thrombocytopenia. A year-old woman with multiple pathology was admitted to the intensive care unit in respiratory distress. Her platelet count fell after 1 week. Heparin was first suspected and withdrawn, without effect. Sildenafil was then withdrawn and the platelet count started to rise.

For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of mg or decreased to 25 mg. The recommended dose for ritonavir-treated patients is 25 mg prior to sexual activity and the recommended maximum dose is 25 mg within a 48 hour period because concomitant administration increased the blood levels of sildenafil by fold see Warnings and Precautions 5. Consider a starting dose of 25 mg in patients treated with strong CYP3A4 inhibitors e. Other brands: Revatio.

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Symptoms often manifest themselves six to ten hours after ascent and generally subside in one to two days, but they occasionally develop into the more serious conditions. Symptoms include headache, fatigue, stomach illness, dizziness, and sleep disturbance. Those individuals with the lowest initial partial pressure of end-tidal pCO 2 the lowest concentration of carbon dioxide at the end of the respiratory cycle, a measure of a higher alveolar ventilation and corresponding high oxygen saturation levels tend to have a lower incidence of acute mountain sickness than those with high end-tidal pCO 2 and low oxygen saturation levels. Headaches are the primary symptom used to diagnose altitude sickness, although a headache is also a symptom of dehydration. The most serious symptoms of altitude sickness arise from edema fluid accumulation in the tissues of the body. The physiological cause of altitude-induced edema is not conclusively established.

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The objectives of this study were to evaluate the efficacy and tolerability of high dose sildenafil as a salvage therapy for patients refractory to the maximum recommended dose of sildenafil. Fifty four fully evaluated patients with chronic erectile failure ED who had previously failed to cheap viagra gels to a home trial of sildenafil mg with erections suitable for sexual intercourse were studied. Each man was treated at home with sildenafil at escalating doses of up to mg until either maximal response or intolerable adverse effects occurred. Erectile function was quantified using the erectile function domain of the International Index of Erectile Function IIEF before treatment, with sildenafil mg and with maximal dose of sildenafil and a global efficacy question after 4 weeks of treatment. The mean age of the study group was Mean IIEF question 3 and 4 scores were 1.

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