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These fuels include diesel produced by the Fischer-Tropsch process, methanol, mixed alcohols methanol, ethanol and others, ethanol, gasoline and dimethyl ether which, like propane, requires modest pressurization to remain liquid. It is the liquid fuel that is most efficiently and inexpensively produced from natural gas. These flexible fuel vehicles could be operated on various mixtures of methanol, ethanol and gasoline. Presently flexible-fuel vehicles are not equipped to operate on methanol. Removing this barrier through the adoption of some type of open fuel standard would be needed for methanol use to be pursued on a level playing field.
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Attacks of gout usually develop very quickly. The first attack often occurs in the middle of the night with the sufferer waking up with extreme joint pain.
- You may find the British Thoracic Society Guidelines useful for this case study.
- Distribution of drugs around the body is likely to be different in older people because of changes in body composition, plasma protein concentration and blood flow to major organs.
- Hyperplasia of the gums and hirsutism can occur.
- Drugs are therefore generally more effective in combination and may act synergistically.
- Examples are streptokinase and alteplase.
- However, opioid analgesics cause respiratory and cardiovascular depression, which is additive to that of general anaesthetics.
- The source of tyrosine is thyroglobulin, a protein synthesized in the thyroid gland.
They act at benzodiazepine receptors that are found close to GABA receptors. GABA receptors are found on chloride ion channels at inhibitory synapses in the CNS, including the RAS (see Figure When chloride channels open, chloride ions flow inwards making the neuronal membrane hyperpolarized.
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Although air and gas can be used to provide negative contrast, positive contrast agents are most commonly used. These are based on iodine or barium molecules which absorb X-rays well.
The Medicines for Human Use Miscellaneous Amendments Order No Office of Sector Information Medicinal Products Prescription by Nurses etc. Act, HMSO, London. Price, R. and Le Masurier, S. Longitudinal changes in extended roles in radiography: a new perspective.
Drugs are therefore generally more effective in combination and may act synergistically. This also means that severe toxicity effects can often be avoided. The drugs should be used at the maximum dose that can be tolerated and as frequently as possible to discourage tumour regrowth. Mechanisms of acquired resistance to cancer chemotherapy include: decreased uptake of drug into cells, or increased expulsion from cells; increased production of substances that can inactivate the drug; increased activity of DNA repair enzymes; increased metabolism and inactivation of the drug; reduced conversion of drug into its active form. All drugs used to treat cancer have a narrow therapeutic ratio and considerable potential for causing serious harm.
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Leucocytes infiltrate into the epidermis and can form microabsesses. All parts of the skin can be involved including mucous membranes and nails, but more usually isolated patches of skin are affected, particularly at the elbows and knees with clear demarcation between the plaques of psoriasis and normal skin.
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Successful therapy requires the prolonged use of a combination of at least three different antibiotics. Treatment of other lung diseases, for example lung cancer, is beyond the scope of this book.
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