What is armodafinil, and how does it work mechanism of action? Armodafinil is an oral drug that is used to promote wakefulness. It is similar to modafinil Provigil. Like amphetamines, armodafinil promotes wakefulness by stimuatIng the brain; however, the exact mechanism of action of armodafinil is unknown. Armodafinil may work by increasing the amount of dopamine a chemical neurotransmitter that nerves use to communicate with each other in the brain by reducing the reuptake of dopamine into nerves. The FDA approved armodafinil in June

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Armodafinil is produced by the pharmaceutical company Cephalon Inc. Because armodafinil has a longer half-life than modafinil does, it may be more effective at improving wakefulness in patients with excessive daytime sleepiness. Armodafinil is currently FDA-approved to treat excessive daytime sleepiness associated with obstructive sleep apnea, narcolepsy, and shift work disorder. In June, it was revealed that a phase II study of armodafinil as an adjunctive therapy in adults with schizophrenia had failed to meet the primary endpoints, and the clinical program was subsequently terminated. In placebo-controlled studies, the most commonly observed side effects were headache, xerostomia dry mouth, nausea, dizziness, and insomnia. Possible side effects also include depression, anxiety, hallucinations, euphoria, extreme increase in activity and talking, anorexia, tremor, thirst, rash, suicidal thoughts, and aggression.

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Armodafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep obstructive sleep apnea. It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine shift work sleep disorder. Armodafinil does not cure these sleep disorders and may not get rid of all your sleepiness. Armodafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how armodafinil works to keep you awake.

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In obstructive sleep apnea, indicated to treat excessive sleepiness and not as treatment for the underlying obstruction. Prior Authorization Drugs that require prior authorization.

This includes narcolepsy, sleep apnea, and shift work sleep disorder. Strength: MG. Color: White. Shape: Oval. NOTE: This sheet is a summary. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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Armodafinil is the R-enantiomer of modafinil which is a mixture of the R- and S-enantiomers. The chemical structure is Armodafinil is a white to off-white, crystalline powder that is slightly soluble in water, sparingly soluble in acetone, and soluble in methanol. Consideration should be given to the use of lower doses and close monitoring in geriatric patients see Use in Specific Populations. North Wales, PA Revised: Feb

As such, they can be accessed and supplied by qualified, registered podiatrists. Wart preparations contain keratolytics such as salicylic acid, formaldehyde or glutaraldehyde, which work by removing the dead skin cells at the surface of the wart. Armodafinil 250mg Use of liquid nitrogen for destroy warts. Multiple treatment over several months. Electrosurgery Under local anaesthetic, the wart is pared away and the base burned by diathermy or cautery. Two weeks to heal.

Org. uk British Nuclear Medicine Society Administration of Pharmaceuticals in Nuclear Medicine http:www. gov. ukenPolicyAndGuidanceMedicinesPharmacyAndIndustry PrescriptionsTheNonMedicalPrescribingProgrammeindex. htm http:www.

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