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The main distinction is that the newer drugs produce fewer motor side effects. Phenothiazines were developed after it was noticed that the antihistamine, promethazine had a sedative action. Chlorpromazine is the most well known and is the standard against which all other anti-psychotics are compared. It is still widely used. Anti-psychotic drugs block dopamine receptors in all four dopamine systems of phentermine 37.5 lowest price brain.

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