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This a common side effect of cytotoxic drugs. Effective haemoglobin synthesis and red blood cell production also depends on the action of a growth factor, erythropoietin, produced by the kidneys.

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Drugdrug interaction This occurs when two or more drugs, being taken concurrently, produce a pharmacological response not attributable to a single drug. The practice of multiple drug prescribing is known as polypharmacy.

The antiemetic effect is due to the blocking of dopamine receptors in the chemotrigger zone of the medulla. The chemotrigger zone is sensitive to potentially harmful chemicals in blood. Adverse effects of metoclopramide include rashes and pruritis. In high dose, injection of metoclopramide can cause sedation and facial muscle spasms due to effects on dopamine receptors in the brain. This is similar to the adverse reactions seen with antipsychotic drugs.

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The mode of action of etoposide is not completely known, but it may be due to an inhibitory effect on topoisomerase similar to that of doxorubicin. Adverse effects of etoposide are nausea and vomiting, cheap sildenafil canada loss and bone marrow suppression. Hormones are used specifically in cancers that are hormone dependent. Growth of such tumours can be suppressed by hormones with the opposite action, by hormone antagonists or by inhibition of hormone secretion. Some examples are shown Hormonal treatment plays an important role in the management of cancers of the breast, prostate and endometrium.


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