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Distribution can also be affected due to differences in body composition and the availability of plasma proteins for binding. At these extremes of life, drugs tend to produce greater and more prolonged effects. Many disease states can cause individual variation in response to drugs. Any disease that results in alteration in the pharmacokinetics of a drug will create these variations.

Authored by Andrew Teffeau, MD


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There is no cure for HIV infection. The aim of drug therapy is to slow or stop disease progression by using a combination of different antiviral drugs.

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