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Gluten sensitivity is a term that is applied interchangeably with intolerance. However, the term should be used to describe patients who can get a variety of symptoms when they eat gluten and feel better on a gluten-free diet but do not have celiac disease. The biopsy is normal and there is no damage to the intestine. Common symptoms of gluten sensitivity include abdominal pain similar to irritable bowel syndrome, fatigue, headaches and paresthesia tingling of the extremities. There is also a possibility that a subgroup of patients with psychiatric disorders like schizophrenia might be affected by gluten sensitivity. The phenomenon of gluten sensitivity is being researched.

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  • Dives aimed at the leisure market will be available on a regular basis from various points on the Costa Brava, while personalised dives can be requested from other locations.
  • Ropivacaine is similar, less potent than bupivacaine but less cardiotoxic and with a longer duration of action.
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  • An example of an anti-cholinergic drug used in Parkinsons disease is benzatropine, but this drug has to be given by injection, either intramuscularly or intravenously.

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For this activity, radiographers have been working within PGDs or in limited cases using PSDs. Technicians are not legally permitted to use PGDs and as such cannot work within them.

Local anaesthetic activity is dependent on pH, because pH determines the degree of dissociation into ions. This becomes of clinical importance in inflamed and infected tissue, which often has a more acid pH. Acid conditions result in increased degree of ionization and reduced diffusion of local anaesthetic into neurons. This makes them less effective anaesthetics. However, it is recommended that local anaesthetics should not be injected into inflamed tissue as this increases absorption into blood and consequently increases the risk of side effects. Neurons are differentially sensitive to local anaesthetics.

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It is activated by tissue plasminogen activator as healing takes place. Small amounts of plasminogen are activated all the time to keep blood vessels free from clots. Haemophilia is a sex-linked recessive inherited disorder of coagulation. There are two types: haemophilia A, or classical haemophilia, is due to lack of Factor VIII and haemophilia B, or Christmas disease, is due to lack of Factor IX. Both diseases have similar symptoms of excessive bleeding from wounds, easy bruising, bleeding into joints, bleeding into the sheath of nerve trunks resulting in paralysis or muscle spasticity, bleeding into the urinary tract and bleeding into the central nervous system. Treatment of both conditions is by replacement of the missing factor.


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High doses of prilocaine can cause methaemoglobinaemia and cyanosis. For this reason, it is used with caution in patients with anaemia, cardiac failure, congenital or acquired methaemoglobinaemia or impaired respiratory function.

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There are many drugs in this group of anti-cancer drugs. Some other examples are busulphan and cisplatin.

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