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Objective: To investigate the toxicity of bupropion hydrochloride in deliberate self-poisoning in adults and accidental ingestion by children. All bupropion overdoses.
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Bupropion Zyban SR was first marketed in Australia late in as a short-term aid to giving up smoking and has had very high usage. It was initially developed as an antidepressant. It is a selective inhibitor of the neuronal re-uptake of catecholamines in the brain but its mechanism to enhance the ability to quit smoking is unknown. In contrast, the very high usage of bupropion in a short time has highlighted several possible adverse effects, some of which may be severe. The assessment of reactions to bupropion use is difficult because many patients experience the effects of nicotine withdrawal in addition to the effects of bupropion.
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Zyban Glaxo Wellcome mg sustained-release tablets Approved indication: nicotine dependence Australian Medicines Handbook Section A controlled trial of sustained-release bupropion, anicotine patch, or both for smoking cessation.
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Tobacco smoking is the leading preventable cause of morbidity and mortality in Australia and other developed countries. Quitting smoking can increase life expectancy of current smokers by 1—7.
- Zyban Glaxo Wellcome mg sustained-release tablets Approved indication: nicotine dependence Australian Medicines Handbook Section
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This could provide timely and appropriate access to treatment for chronic disease management. A community physiotherapist treating a patient in a remote location who is not responding well to medicines prescribed by a consultant could, under a CMP, alter dosages for that patients benefit.
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Each amino acid is coded for by a sequence of three bases, known as bupropion online australia triplet code. For example, ACA codes for the amino acid cysteine. As amino acids are added in sequence a protein is built up. The aim of chemotherapy is either, to affect a cure by reducing the size of a tumour so that it can be surgically removed or it disappears altogether, or to prolong life and provide palliative care. For the best chance of success, drugs must be used early on in a patients treatment along with irradiation or surgery when the cancer is most curable and the patient is most able to tolerate treatment.
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An anxiolytic is a drug that reduces feelings of anxiety, whereas a hypnotic is a drug that induces sleep. The two terms are interchangeable in the sense that most anxiolytics will induce sleep when given at night and most hypnotics will cause sedation when given during the day.
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The site of action is in the brain, probably the medulla, and the effect is to reduce sympathetic output. Examples of centrally acting antihypertensives are methyldopa and clonidine.
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Otto
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