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The frequency of contrast agent injection and dose are known risk factors for renal toxicity. Ideally, in patients at high risk of renal toxicity, there should be five days between administrations and the lowest possible dose of either non-ionic monomer or non-ionic dimer should be used.
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BNMS explains that it allows locally written protocols to be used for the administration of adjunct medicines and in essence, these might look similar to PGDs.
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Most antidepressants lead to the production of brain-derived neurotrophic factors that bring about neurogenesis and this could contribute to their effectiveness in depressed patients.
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