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This, in combination with a reduction in both afterload and preload (dilation of veins), relieves the angina. Nicorandil is an example of a potassium channel activator.
- It is also formulated in combination with a sulphonamide, when it is known as co-trimoxazole, to treat pneumonia in patients with HIV.
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- Gabapentin was designed as a GABA analogue and is an effective anticonvulsant but it does not work on GABA receptors.
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- See Figure Here the immune complexes can cause a local inflammation by activation of the complement system.
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The abnormal activity may be due to increased excitatory neuronal transmission, possibly involving abnormal sodium ion channels or decreased inhibitory transmission, possibly due to abnormality at GABA receptors. Certainly, most antiepileptic drugs either block sodium ion channels or enhance the action of GABA or both. Alzheimers disease is characterized by atrophy of the cerebral cortex and loss of neurons, leading to gradual decline in intellectual ability and short-tem memory. There is no cure for Alzheimers disease, but treatment with central acetylcholinesterase inhibitors aims to enhance cholinergic transmission and glutamate blocking drugs reduce the possibly damaging effects of glutamate. This is a long chapter and as such warrants several case studies.
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Muscle relaxants and analgesics are used as adjuncts to anaesthesia, respectively to cause muscle relaxation and aid surgery and to reduce patient discomfort post-operatively. Local anaesthetics are also known as local analgesics because they cause the loss of the sensation of pain in a part of the body.
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Sieglinde
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Following European Directive European Law requires the use of the recommended International Non-proprietary Name (rINN).
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Formation of emboli is a risk in either case.
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Eugen
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