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- All local anaesthetics block sodium ion channels so that sodium ions cannot flow into neurons.
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Adverse effects of cyclosporin are toxicity to bone marrow, nausea, leukopenia, blurred vision and rashes.
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Alternatively, a drug could be metabolized faster than expected into a toxic compound. The mechanisms involved in enzyme induction are unclear but somehow DNA sequences are affected so that production of the relevant enzyme is increased.
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Myasthenia gravis is an autoimmune disease where acetylcholine receptors at the neuromuscular junction are progressively destroyed.
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