Zopiclone
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Zopiclone is molecularly distinct from benzodiazepine drugs and is classed as a cyclopyrrolone. However, zopiclone increases the normal transmission of the neurotransmitter gamma-aminobutyric acid GABA in the central nervous system, via modulating benzodiazepine receptors in the same way that benzodiazepine drugs do. |
It is used for the short-term and symptomatic relief of sleep disturbances. Nonmedicinal ingredients: corn starch, dicalcium phosphate, lactose, magnesium stearate, and sodium carboxymethyl starch; coating: hydroxypropyl methylcellulose and titanium dioxide. |
Zopiclone is used to treat short-term sleep problems or insomnia. |
It is used for the short-term and symptomatic relief of sleep disturbances. |
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Short term treatment of insomnia, including difficulties in falling asleep, nocturnal awakening and early awakening, transient, situational or chronic insomnia, and insomnia secondary to psychiatric disturbances, in situations where the insomnia is debilitating or is causing severe distress for the patient. |
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Since zopiclone is a water insoluble drug, various methods such as co-solvency, pH control and hydrotrophy have been tried in order to enhance its solubility. |
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