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The abnormal product then brings about the action of the original drug. Methyldopa can be used again as an example here. It is a false substrate for the enzyme that normally converts dopa into dopamine. Some drugs need conversion by an enzyme from an inactive pro-drug into an active form before they can be of therapeutic use. Methyldopa, above, could be said to be a prodrug and methylnoradrenaline the active drug. Drugs are capable of producing adverse reactions as well as beneficial therapeutic effects.
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It works by damaging the head of the tapeworm so that it can no longer attach to the inside of the intestine. Niclosamide has few side effects, but it has been superseded by praziquantel.
03.06.2020
Johannes
Verified
In some cases where there is involvement of only a few joints, corticosteroids (usually triamcinolone or hydrocortisone) can be administered locally by intra-articular injection to relieve pain, increase mobility and reduce deformity. Methylprednisolone has recently been added to the list of drugs that registered podiatrists can administer by injection into soft tissue injury.
03.11.2016
Jan
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It should not be used in patients who have glaucoma or an enlarged prostate as it will make both of these conditions worse.
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Glyceryl trinitrate is extremely effective at relieving the pain of angina but it has only a short half-life. Due to extensive first pass metabolism the drug is ineffective when taken orally and is administered sublingually or buccally in either tablet or aerosol form.
08.06.2017
Georg
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