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The Spanda Foundation has a cross-cultural goal aiming at a better understanding among people to stimulate cultural diversity. We intend to achieve this through dialogue and a deeper knowledge of mutual cultures, ideas, traditions, faiths and beliefs. At the heart of this mission is an aspiration to contribute to the achievement of a higher individual and collective state of consciousness. The Foundation is active in promoting individual, social, economic and global development by means of initiatives and project in the areas of culture, education, health, the environment, economics and research. Our projects and initiatives add social value by fostering creative solutions that may advance human progress and enrich communities towards a more just, sustainable and peaceful world by serving the common good. The Foundation acts in an advisory capacity to governments, parliaments and social organization. Spanda is particularly interested in projects that encourage freedom of inquiry, imagination, insight, creativity and expression.

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These viruses use an enzyme called reverse transcriptase to copy viral RNA to produce viral DNA. The viral DNA is then incorporated into the host cells DNA where it can lie dormant before being used as a template for the production of more viral RNA. Drugs have been developed to inhibit reverse transcriptase and are used particularly to treat HIV. Some drugs in this group are also nucleoside analogues; others are not. Zidovudine is a thymidine analogue and was the first drug introduced that inhibits reverse transcriptase.

The site of action of anti-cholinergic drugs appears to be at muscarinic receptors in the basal nuclei. However, as the disease progresses, the loss of dopaminergic activity becomes so great that anti-cholinergic drugs cannot compensate for it. An example of an anti-cholinergic buy alprazolam online legally used in Parkinsons disease is benzatropine, but this drug has to be given by injection, either intramuscularly or intravenously. Trihexyphenidyl is an anti-cholinergic drug that can be given orally. Anti-cholinergic drugs are most effective against tremor, but less so at improving muscle rigidity and hypokinesia.

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Sustained release forms are available to provide prophylactic action against angina attacks; these are formulated into transdermal patches. Isosorbide dinitrate and isosorbide mononitrate are more stable forms of nitrate and have a longer lasting effect than GTN making them more suitable for prophylaxis of angina. They are taken orally. When used prophylactically, tolerance may develop to the vasodilator effects of nitrates. To avoid this, patients have to have drug free periods each day, when they know they are least likely to suffer and angina attack. Typical adverse effects include headache, postural hypotension and flushing, which often restrict the use of nitrates.

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These are used prophylactically postoperatively and in people who have already had a thrombotic episode. They are most effective at preventing venous thrombosis. Vitamin K antagonists block the activity of vitamin K resulting in the production of inactive clotting factors by the liver. They take a few days to have effect xanax rx online circulating clotting factors already in existence have to be used up. Examples of vitamin K antagonists are warfarin and phenindione (normally used only when patients cannot tolerate warfarin).

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Patient information leaflets must be included in packaging of medicines. All drugs have at least three names: the chemical name, the generic name and the proprietary name. Chemical names can be complicated and difficult to buy alprazolam online legally and are not used in this book. A generic name is a drugs official name and the majority of drugs in this book are referred to by their generic names. The proprietary name is the name given to a drug by the manufacturing company.

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An example of an adrenergic neurone blocker is guanethidine. Adverse effects include postural hypotension, bradycardia and fluid retention.

  • There are many proprietary preparations, which are more refined and therefore more acceptable to patients, but they are less effective.
  • This in turn reduces peripheral vascular resistance and they are used to reduce blood pressure.
  • Drugs are therefore generally more effective in combination and may act synergistically.
  • Corticosteroids can be useful in reducing acute exacerbations of chronic bronchitis.
  • The terminal bronchioles divide into alveolar ducts at the end of which are tiny thin walled air sacs, the alveoli.
  • In addition, giving alone or in combination with chlorimipramine seems to benefit these patients.
  • On subsequent exposure to the same allergen the combination of IgE and allergen causes the mast cells to release a variety of chemicals including histamine.

The reasons for this are not know, but suggestions include nicotine induction of detoxifying enzymes, inhibition of harmful enzymes or stimulation of factors that protect neurons. Treatment of Parkinsons disease is not usually started until symptoms are interfering with daily life and should be initiated under supervision of a specialist.

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Bacterial pneumonia can be treated with antibiotics such as the ones given above under cystic fibrosis, depending on the infecting organism. Viral pneumonia is uncommon and not usually serious unless it occurs in the very young, the very old, those with chronic lung disease or the immunocompromized.

This means that most drugs are subjected to some kind of metabolism and then excreted. Metabolism involves changes to the molecular structure of a substance and these changes are produced by the action of enzymes. This has two important effects on drug molecules: kidneys; This is not always the case. A drug metabolite may have a new and completely different pharmacological activity, or it may be as active as or more active than the original drug. Some drugs have to be metabolized in order to become active. Prodrugs are drugs that have been designed to remain inactive until they have been metabolized by the body.

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In these cases, specialist treatment with drugs that suppress the immune system may be required. These drugs are normally used to prevent transplant rejection. For severe eczema refractory to other treatment, ciclosporin is licensed for oral use and tacrolimus is licensed for topical use. Adverse effects of cyclosporin are toxicity to bone marrow, nausea, leukopenia, blurred vision and rashes. Adverse effects of topical application of tacrolimus are rash, irritation, pain and paraesthesia. Psoriasis is a chronic inflammatory skin disease affecting about The condition is characterized by hyperproliferation of keratinocytes.


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Strictly speaking, motor neuron disease and multiple sclerosis are diseases of the nervous system, rather than the musculoskeletal system.

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Topical treatments include drugs that reduce cell division, such as calcipotriol, dithranol and coal tar, and keratolytics and emollients.

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Drug interaction is not always an adverse reaction.

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An organism called Pneumocystis cariniiwhich used to be classified as a protozoan, causes this type of pneumonia.

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Some are due to the inhibition of other functions of microtubules. Thus migration of white blood cells and axonal transport in neurons are inhibited leading increased susceptibility to infection and neurotoxicity respectively.

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