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Prior to the from natural sources. Examples of drugs originally from natural sources and still in use today are quinine, digitalis (from the foxglove and used for heart failure) and aspirin (extracted from the bark of willow tree and originally used to treat fever). Development of new drugs can happen in many ways. Drugs have been developed following observation of side effects when being used for other purposes.
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Particular areas of the central nervous system affected are the optic nerves, brain stem and cerebellum, corticospinal tracts of the spinal cord and areas around the ventricles. Demyelination leads to variable symptoms depending on where the lesions are.
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Since vitamin D normally enhances calcium absorption from the intestines and its release from bone, hypercalcaemia is a potential side effect. However, only rarely is sufficient amounts of drug absorbed to affect calcium homeostasis in this way.
26.11.2020
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Early use of disease-modifying antirheumatic drugs can prevent disease progression and limit joint damage.
28.11.2019
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