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The two polynucleotide strands of DNA coil around each other so that the bases project towards the inside of the helix. The structure is held in place by bonds that form between complementary bases. Adenine can only pair with thymine and guanine can only pair with cytosine.
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Carcinogenesis is the occurrence of drug-induced tumours. This can happen through damage to DNA causing mutation of genes, activation of proto-oncogenes or damage to oncogene suppressors. Due to strict testing of new drugs during the developmental stages this should be a rare phenomenon. However, some drugs through immunosuppression, are known to increase the risk of tumour formation. For example, drugs used to treat cancers and drugs used to prevent transplant rejection are known to do this.
Steam inhalation may be as effective as a mucolytic in chronic bronchitis. Drugs used to treat asthma and chronic bronchitis are summarized Although asthma is considered to be a reversible condition, severe acute attacks can cause obstruction that can take days to reverse and in some cases is not reversible at all. Such attacks need to be treated as a medical emergency requiring hospital treatment. Treatment includes oxygen, inhalation of salbutamol in oxygen, intravenous hydrocortisone and oral prednisolone.
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Authored by Jason Lentz, MD
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The rate at which a drug is metabolized will affect its distribution. Similarly the rate of elimination or excretion also affects distribution and vice versa.
18.05.2017
Kriemhild
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Although generally not as important as renal excretion, other routes of excretion account for elimination of some drugs.
23.12.2019
Martin
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This effect, which can be repeated many times, prolongs the duration of action of the drug until it is eventually excreted by the kidneys.
23.03.2019
David
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The centre of gravity is forward and the patient walks on the front of the feet with quick short steps. There is difficulty in initiating movements and stopping once movement has begun.
20.08.2020
Wilhelm
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