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As the ventricle contracts blood leaves via the aorta passing through the aortic valve. Blood flow through the heart and round the body is maintained by contraction of the atria in unison followed by contraction of the ventricles in unison.
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Coagulation disorder can be secondary to liver disease because most clotting factors are synthesized in the liver. Vitamin K is essential for successful formation of many clotting factors so lack of vitamin K can cause a coagulation disorder.
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Therapy therefore aims to improve dopaminergic transmission or inhibit cholinergic pathways to restore the balance.
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Certainly, the genesis of cancer involves many factors working together. Characteristics of cancer include uncontrolled cell division with excessive growth of undifferentiated cells.
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