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A commonly used example of this type of diuretic is bendroflumethiazide. Loop diuretics inhibit sodium and chloride ion transport in the ascending limb of the loop of Henl´e and therefore prevent water reabsorption there.

  • These drugs aim to eliminate the resting stage of the parasite in the liver.
  • Chlorpromazine is the most well known and is the standard against which all other anti-psychotics are compared.
  • Department of Health Medicines Matters: A Guide to Mechanisms for the Prescribing, Supply and Administration of Medicines, National Practitioner Programme Department of Health Core Prescribing Group, London.
  • Other areas of research include the development of drugs that block the capacity of oncogenes to turn cells malignant; antagonists of growth factors; inhibitors of cell cycle control factors; and gene therapy to restore tumour suppressor gene function.

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Some examples are given below. Procarbazine inhibits RNA and DNA synthesis and interferes with mitosis. It is a drug that interacts with alcohol and generally increases the effects of central nervous system depressants and can produce hypertension.

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Authored by Dr. John Anthony Goncalves, MD


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Pharmacology as a science encompasses the following: the action of natural chemicals in the body; the origins and sources of drugs; their chemical structure and physical characteristics; their mechanisms of action; their metabolism and excretion; studies of their action on whole animals, isolated organs, tissues and cells, enzymes, DNA and other components of cells; ultimately studies of their actions in humans and their therapeutic uses.

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These drugs are potent coronary vasodilators and can increase blood flow to the myocardium.

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