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Inactivation of a neurotransmitter can be by re-uptake into the neuron it was released from, or by the action of enzymes in the synaptic cleft. NB While the exact involvement of a particular neurotransmitter in a particular CNS disorder is unknown, a question mark denotes more uncertainty about the neurotransmitter involvement.
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Penicillin used to be administered together with probenecid. Probenecid is slowly transported by the same system and therefore considerably reduces the elimination of penicillin.
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