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These medications may be counterfeit and potentially unsafe. Exclusivity is the sole marketing rights granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent.

Due to the existence of these factors, it is unsatisfactory simply to adjust doses for children because of weight alone. For the majority of drugs that have a low TR dose adjustment is best made in relation to metabolic rate, which can be estimated from body surface area. However, specialist knowledge is needed in this area. A special edition of BNF for Children is now produced. Unexpected reactions to drugs can occur in children.

The advantages of physiotherapy supplementary prescribing in the community are that both patients and physiotherapists benefit in many ways. For example instead of having to be referred back to a doctor and having to make another journey, a patient could be managed by the physiotherapist. This could provide timely and appropriate access to treatment for chronic disease management. A community physiotherapist treating a patient in a remote location who is not responding well to medicines prescribed by a consultant could, under a CMP, alter dosages for that patients benefit. Specialist knowledge allows the physiotherapist to explain to patients in these situations how to take their medication for best effect and could help improve compliance.

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