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Inhibition of this enzyme in the brain increases the amount of acetylcholine available and prolongs its action. These drugs produce a modest improvement in memory or slow progression of symptoms in some patients.

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Eventually, whether metabolized or not, a drug is eliminated from the body. The usual route of excretion is via the kidneys and rate of elimination depends on rate of urine production, pH of urine and transport mechanisms. Although drugs do appear in faeces, expired air, sweat and breast milk, these are normally minor routes of excretion. The following two case studies could be of relevance to any health care professional. Mr Robinson is a every from which he seems to be recovering well. He tells you that his doctor at the hospital has put him on a new drug to thin his blood and told him that he must not drink alcohol.


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