The originating document has been archived. UK Edition. If you have any further questions, ask your doctor or pharmacist. This medicine has been prescribed for you. If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. What Diazepam is and what it is used for 2. Before you take Diazepam 3.

As an anxiolytic, the lowest effective dose should be employed; dosage regimes should not exceed beyond 4 weeks and treatment should be gradually withdrawn. Patients who have received benzodiazepines for a long time may require an extended withdrawal period. Long-term chronic use is not recommended. Anxiety states, obsessive-compulsive neuroses, and other psychiatric disorders: mg daily in divided doses. Muscle spasm of varied aetiology, fibrositis, cervical spondylosis: mg daily in divided doses. Oral premedication in dental patients: 5mg the night before, 5mg on waking and 5mg two hours before the appointment.

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Diazepam is one of the most commonly prescribed sedative drugs for the treatment of anxiety, convulsions, and muscle spasms. From: Handbook of Pharmacogenomics and Stratified Medicine, Diazepam produces less sedation in cigarette smokers, and higher doses may be required for the same sedative or anxiolytic effect. These include cases of urinary retention and compartment syndrome, which are not explicable by its pharmacology. It is slowly and incompletely absorbed after intramuscular administration.

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Valium may be used alone or with other medications. These are not all the possible side effects of Valium. Valium diazepam is a benzodiazepine derivative. It is a colorless to light yellow crystalline compound, insoluble in water. Valium is available for oral administration as tablets containing 2 mg, 5 mg or 10 mg diazepam. Valium 2-mg tablets contain no dye.

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Common side effects include sleepiness and trouble with coordination. Arsenic poisoning Dimercaprol Succimer.

COVID is an emerging, rapidly evolving situation. It is known that benzodiazepines have a hypotensive effect, but the mechanism has not been well elucidated yet. To clarify whether this effect is due to central or peripheral mechanism, we administered 5 mg of diazepam or saline intravenously to healthy volunteers and assessed the change in blood pressure, heart rate, muscle sympathetic nerve activity and heart rate variability. After diazepam administration, systolic and mean blood pressure decreased significantly. We concluded that the hypotensive effect of diazepam in human is mainly due to the central mechanism.

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Common side effects include sleepiness and trouble with coordination. Diazepam was patented in by Hoffmann-La Roche. Diazepam is mainly used to treat anxiety, insomnia, panic attacks and symptoms of acute alcohol withdrawal. It is also used as a premedication for inducing sedation, anxiolysis, or amnesia before certain medical procedures e. Benzodiazepines have a relatively low toxicity in overdose. Dosages should be determined on an individual basis, depending on the condition being treated, severity of symptoms, patient body weight, and any other conditions the person may have.

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This effect can be counteracted by a high intake of fluid and by using a drug called mesna. Otherwise, cyclophosphamide can cause bone marrow depression, sterility and increased risk of other cancers. There are many drugs in this group of anti-cancer drugs. Some other examples are busulphan and cisplatin. Antimetabolites block or alter a metabolic pathway involved in Diazepam b.p 5mg synthesis.

The chief adverse effect of anticoagulants is haemorrhage; hypersensitivity reactions are also possible. Platelet diazepam b.p 5mg are most effective in preventing arterial thrombosis. Aspirin reduces platelet aggregation by inhibiting the enzyme cyclo-oxygenase, which is necessary for the formation of thromboxane A in patients with heart disease such as angina and arrhythmia as well as those with previous thrombotic disease. Dipyridamole has a similar effect on cyclo-oxygenase as aspirin. Clopidrogel is another platelet inhibitor that works by inhibiting ADP-induced aggregation.

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