A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. From Martindale, The Extra Pharmacopoeia, 30th ed, p Combining diazepam, a proven effective therapy for acute repetitive seizures, with an auto-injector designed for subcutaneous administration that is quickly and easily administered offers the potential for complete, consistent drug absorption and rapid onset of effect 7. This current development is subsequently an important addition to the rescue therapy tool chest for patients with epilepsy 7. In general, diazepam is useful in the symptomatic management of mild to moderate degrees of anxiety in conditions dominated by tension, excitation, agitation, fear, or aggressiveness such as may occur in psychoneurosis, anxiety reactions due to stress conditions, and anxiety states with somatic expression.

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Diazepam may increase the risk of serious or life-threatening breathing problems, sedation, or coma if used along with certain medications. Your doctor may need to change the dosages of your medications and will monitor you carefully. Drinking alcohol or using street drugs during your treatment with diazepam also increases the risk that you will experience these serious, life-threatening side effects. Do not drink alcohol or use street drugs during your treatment. Diazepam is used to relieve anxiety and to control agitation caused by alcohol withdrawal.

Common side effects include sleepiness and trouble with coordination. Diazepam was patented in by Hoffmann-La Roche. Diazepam is generic brand for diazepam used to treat anxiety, insomnia, panic attacks and symptoms of acute alcohol withdrawal. It is also used as a premedication for inducing sedation, anxiolysis, or amnesia before certain medical procedures e. Benzodiazepines have a relatively low toxicity in overdose.

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Myasthenia gravis. Severe respiratory insufficiency. Severe hepatic insufficiency. Sleep apnea syndrome. Acute narrow-angle glaucoma.

DOI: Locniskar and D. Greenblatt and J. Harmatz and R. Locniskar, D. Create Alert.

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What Is Valium? Valium diazepam is a benzodiazepine prescribed for the treatment of anxiety, seizures, muscle spasms, and symptoms of alcohol withdrawal. Valium is available as a generic drug. Drug interactions with Valium include alcohol, barbiturates, and narcotics, cimetidine Tagamet, ketoconazole Nizoral, omeprazole Prilosec fluvoxamine Luvox, and fluoxetine Prozac. Valium use during pregnancy may cause adverse effects in the fetus and it is secreted in breast milk so it should be avoided while breastfeeding.

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Bipolar depression is depression that alternates with periods of mania. Patients with bipolar depression are generally younger at the outset than those with unipolar depression and are less likely to suffer from agitation and anxiety, suggesting a different biochemical abnormality to unipolar depression. Bipolar depression tends to run in families, so there may be a genetic element to its aetiology. First-degree relatives of patients with bipolar depression are more likely to develop mood disorders than relatives of those who do not have bipolar depression. Twin studies have shown concordance rates for bipolar depression of more than twins.

There are many growth factors and they are coded for by genes. Some of these genes are generic brand for diazepam as proto-oncogenes. They were given this name because they can be altered by mutation, carcinogens or viruses to become oncogenes. Oncogenes are capable of causing malignant transformation in cells. An example of a proto-oncogene is the ras gene. This gene codes for a protein called Ras.

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