As an anxiolytic, the lowest effective dose should be employed; dosage regimes should not exceed beyond 4 weeks and treatment should be gradually withdrawn. Patients who have received benzodiazepines for a long time may require an extended withdrawal period. Long-term chronic use is not recommended. Anxiety states, obsessive-compulsive neuroses, and other psychiatric disorders: mg daily in divided doses. Muscle spasm of varied aetiology, fibrositis, cervical spondylosis: mg daily in divided doses. Oral premedication in dental patients: 5mg the night before, 5mg on waking and 5mg two hours before the appointment. Alternative presentations of diazepam are recommended for paediatric usage in order to obtain suitable doses of less than 5mg.

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Valium may be used alone or with other medications. These are not all the possible side effects of Valium. Valium diazepam is a benzodiazepine derivative. It is a colorless to light yellow crystalline compound, insoluble in water. Valium is available for oral administration as tablets containing 2 mg, 5 mg or 10 mg diazepam. Valium 2-mg tablets contain no dye. Valium is indicated for the management of anxiety disorders or for the shortterm relief of the symptoms of anxiety.

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As with other benzodiazepines, diazepam should be used with caution in patients with pulmonary disease. Additionally, avoid coadministration with other CNS depressants, especially opioids, unless no other alternatives are available as coadministration significantly increases the risk for respiratory depression, low blood pressure, and death. Oral diazepam tablets are contraindicated for use in those with severe respiratory insufficiency or sleep apnea syndrome. Diazepam should be used with caution in other pulmonary diseases as well including severe chronic obstructive pulmonary disease COPD, sleep apnea, asthma, or pneumonia because the drug can exacerbate ventilatory failure. Lower doses are recommended in patients with chronic respiratory insufficiency. Use lower initial adult doses for the debilitated adult patient.

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Diazepam is used to relieve symptoms of anxiety and alcohol withdrawal. This medicine may also be used to treat certain seizure disorders and help relax muscles or relieve muscle spasm. Diazepam is a benzodiazepine. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.

A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. From Martindale, The Extra Pharmacopoeia, 30th ed, p Combining diazepam, a valium 10 mg oral tablet effective therapy for acute repetitive seizures, with an auto-injector designed for subcutaneous administration that is quickly and easily administered offers the potential for complete, consistent drug absorption and rapid onset of effect 7.

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Common side effects include sleepiness and trouble with coordination. Diazepam was patented in by Hoffmann-La Roche. Diazepam is mainly used to treat anxiety, insomnia, panic attacks and symptoms of acute alcohol withdrawal. It is also used as a premedication for inducing sedation, anxiolysis, or amnesia before certain medical procedures e. Benzodiazepines have a relatively low toxicity in overdose. Dosages should be determined on an individual basis, depending on the condition being treated, severity of symptoms, patient body weight, and any other conditions the person may have.

In normal lipid metabolism, lipids in the diet are converted to triglycerides, which are used in muscle and adipose tissue. Cholesterol is used for valium 2mg tablets synthesis of steroid hormones and bile acids and by all cells as part of the cell membrane. Lipids do not dissolve easily in water. Therefore, they have to be transported in blood as lipoproteins. Lipoproteins are formed from a protein envelope, made of apoprotein, containing a variable mix of triglycerides and cholesterol.

It is treated as an emergency with dantrolene, which causes muscle relaxation. Nitrous oxide has a low potency and must be valium 10 mg oral tablet in combination with other inhalation anaesthetics for general anaesthesia. Nitrous oxide provides rapid induction and recovery. It also has an analgesic action and is used as a analgesia without loss of consciousness during labour and manipulations of injured body parts. Adverse effects of nitrous oxide are the risk of bone marrow depression with repeated or prolonged use and megaloblastic anaemia due to interference with the actions of vitamin B The mechanism of action of intravenous anaesthetics is thought to be by enhancement of inhibitory pathways or inhibition of excitatory pathways in the brain.

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