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Drugs have been developed against two of them, tumour necrosis factor α (TNF-α) and interleukin and together they are key players in the inflammatory response. Levels of both are raised in rheumatoid arthritis and other autoimmune diseases. Cytokine inhibitors are relatively new and they must only be prescribed under specialist supervision. Their use is still being monitored by the Medicines and Healthcare Products Regulatory Agency. Treatment should be withdrawn if there are severe side effects or no obvious improvement after three months.
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The history and development of non-medical prescribing is explained together with consideration of the different forms this can take, for example supplementary and independent prescribing. The current situation regarding access, supply and prescription of medicines by physiotherapists, radiographers and podiatrists is discussed. There are a number of pieces of legislation concerned with the sale, supply and use of drugs.
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Radiographers who inject contrast agents must be trained in emergency treatment of severe adverse reactions and basic life support. The most severe adverse reaction is anaphylactic shock. This is treated as an emergency with adrenaline, atropine and oxygen.
A monoclonal antibody that inhibits vascular endothelial growth factor already exists for use in metastatic colorectal cancer. There are serious side effects, such as gastrointestinal perforation and impaired wound healing, and its use is being monitored by the MHRA. Other areas of research include the development of drugs that block the capacity of oncogenes to turn cells malignant; antagonists of growth factors; inhibitors of cell cycle control tramadol 50 mg 1mg and gene therapy to restore tumour suppressor gene function.
Side effects of topical use of acyclovir are transient stinging or burning of the skin. Antiviral drugs are discussed in Chapter Organisms called dermatophytes cause the majority of generic tramadol online fungal infections of the skin, hair and nails. The most common dermatophytes that infect humans belong to the trichophyton, epidermophyton and microsporum families. These fungi are commonly occurring in the environment and they thrive in tissues that contain keratin. Such fungal infections of the skin are known as tinea: Tinea pedis is infection of the foot (athletes foot); tinea corporis is infection on the body and tinea capitis is infection of the scalp.
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A drug commonly given by inhalation for a local effect is salbutamol, used to treat asthma. Many general anaesthetics are given in gaseous form clearly intended to have a systemic effect.
- Bacterial pneumonia can be treated with antibiotics such as the ones given above under cystic fibrosis, depending on the infecting organism.
- All drugs have at least three names: the chemical name, the generic name and the proprietary name.
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- A number of drugs are used as adjuncts to radiography.
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Further developments in prescribing for health care professionals came with the advent of supplementary prescribing in Medicines Order and NHS Regulations, podiatrists, physiotherapists and radiographers can now train to prescribe in partnership with and independent prescriber (a doctor or dentist) according to an agreed CMP. The initial take up of supplementary prescribing has been slow in the three health care professions.
Authored by Andrew Teffeau, MD
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Sickle cell disease and thalassaemia are examples of inherited haemolytic anaemias. Sickle cell disease is caused by a gene that codes for an abnormal kind of haemoglobin.
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