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Any disease that results in alteration in the pharmacokinetics of a drug will create these variations. Diseases of the liver and kidney, any disease that affects intestinal motility, mal-absorption syndromes and any condition that reduces plasma protein concentration are all implicated.
26.09.2018
Wolfram
Verified
Some drugs, for example phenytoin, oral contraceptives and isoniazid, can cause reduced absorption of folic acid. Oral replacement therapy with folic acid is effective.
22.11.2016
Agathe
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