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We were blown away by not only the quantity of photos but also the quality. Across the country, roads were closed as picnic blankets and tables were laid out, piled high with food and goodies as over, neighbours chose to turn off their tellies, leave their houses and take to the streets to meet. Competition time! And boy, do we have some good prizes lined up. Fancy winning some of them?
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Touring caravan holidays are holidays to remember. We're going to explain the top 5 reasons why caravan touring is a great idea for a holiday. When you holiday in a Caravan, you don't have to worry about leaving home comforts behind, because the caravan is your home! No worrying about luggage weight and hand luggage, anything you can fit in your caravan you can take with you. Unlike camping with tents, you have all the homely amenities you need, while at the same time, you can step right out of your caravan and into nature, giving you the perfect balance of a camping experience without the confines of a tent and inclement weather.
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Praziquantel is a highly effective anthelmintic, which induces muscular contraction and spastic paralysis in trematodes and cestodes by increasing calcium ion fluxes. Adverse effects are rarely of any clinical importance. Ivermectin is mostly used to treat filariasis and onchocerciasis, which are parasitic worm infections not seen in the United Kingdom. Filariasis causes elephantiasis (blockage of lymphatics and swelling of the limbs) and onchocerciasis causes river blindness in tropical and subtropical countries. Ivermectin has occasional use against round worms, hookworms and whip worms and is available on a named-patient basis in the United Kingdom.
Its mode of action is not known. Side effects are gastrointestinal disturbances and headache. Halofantrine can also cause cardiac arrhythmia and should be avoided in patients with arrhythmias. These drugs aim to eliminate the resting stage of the parasite in the liver. Not all forms of malaria have a resting stage in the liver P. falciparum does not.
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Loss of intracellular potassium ions in particular leads to cell death. Amphotericin is used to treat systemic fungal infections.
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