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The independent prescriber is responsible for the initial diagnosis of a patient and the contents and conditions of their CMP, although they need not write it personally. Within the limits of a CMP, the supplementary prescriber may be able to alter the choice of medicine, the dosage, the frequency of administration and other variables. As an alternative to listing medicines individually, the CMP may refer to recognized and accepted local or national clinical guidance in written or electronic form. Any guidelines referred to should be easily available to all concerned in the patients care ( CMP must include). Supplementary prescribing must include arrangements for regular clinical review of the patients progress by the independent prescriber, at appropriate predetermined intervals, depending on the patients condition and the medicines prescribed for them.

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