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We selected tramadol as a representative drug to address our objective because it is widely prescribed as an unscheduled opioid analgesic and can easily be purchased from NPOPs.



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- Drug therapy of disease is ever expanding; new drugs exist for effective treatment or cure of more diseases than ever before.
- Increase in levels of these two transmitters in the prefrontal cortex is thought to increase inhibitory control in the limbic system.
- Membrane stabilizers are used to treat arrhythmia.
- To avoid this patients should be treated with allopurinol first.
- In this case, in addition to the concentration gradient, a membrane protein acts as a carrier to transport a substance from one side of the membrane to the other.
- The law says who can and cannot prescribe medicines and allows health care professionals to administer and supply medicines to certain patients under PGDs.
Non-nucleoside reverse transcriptase inhibitors such as efavirenz and nevirapine are similar and have a similar profile of adverse effects. Viral protease is essential in retroviruses for the production of mature viral particles.
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Adverse effects of lidocaine are drowsiness, slurred speech, paraesthesia (pins and needles) and convulsions. Flecainide is an alternative to lidocaine for the treatment of ventricular arrhythmia and can be used orally for disabling paroxysmal atrial fibrillation.
Many nutrients and a few drugs can pass across the cell membrane by facilitated diffusion. In this case, in addition to the concentration gradient, a membrane protein acts as a carrier to transport a substance from one side of the membrane to the other. Carrier proteins are specific and only transport molecules that they recognize. Glucose enters many body cells by facilitated diffusion and the process appears to be more efficient than simple diffusion. Carrier systems exist for the transport of some amino acids and vitamins and the same carrier can transport drugs that are structurally similar to them.
Bacteriostatic antibiotics inhibit bacterial growth and proliferation, while bactericidal antibiotics actually kill bacteria. Many antibiotics are bacteriostatic at low concentrations and bactericidal at higher concentrations. This distinction is often not important clinically. If bacteria are prevented from multiplying, they will eventually be destroyed by the normal immune reaction of the host. Infections in immunocompromized individuals (for example, those with human immunodeficiency virus infection and those on systemic corticosteroid, anticancer or immunosuppressant therapy) have to be treated with potent bactericidal drugs.
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A type A adverse drug reaction is a possibility if a patient is given a higher than recommended dose for any particular route of administration due to practitioner error. In order to avoid this it is good clinical practice for drug dosages to be checked by another member of staff prior to administration.
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Malaria is caused by several species of protozoa called plasmodia.
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The skin is the largest organ of the body and forms a barrier between the external environment and the internal organs of the body. The skin is subject to trauma and damage.
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In this condition, there is polyarthritis and vasculitis of small and medium sized blood vessels throughout the body.
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