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Cyclophosphamide produces severe nausea and is often used with a ondansetron. Cyclophosphamide is metabolized to a toxic metabolite called acrolein, which can cause haemorrhagic cystitis, a rare but serious complication.
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The pharmacology content of the training courses will include general principles of pharmacology: absorption, distribution, metabolism and excretion; individual variation to drug therapy, adverse drug reactions, drugdrug interactions, interactions with other diseases and drug interaction with receptors and the legal basis for prescribing, supply and administration of medicines, including regulatory aspects of controlled drugs.
Employers are expected to recognize the need for private study time and to generally provide support.
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Other benefits may be had through increased direct patient contact, and the opportunity to expand services to patients.
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Twin studies have shown concordance rates for bipolar depression of more than twins.
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