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It was first developed by Merck for the treatment of prostate enlargement. Unlike Rogaine — another common hair loss drug found on the market — finasteride works from the inside out. In short, it interrupts the process that converts testosterone the male sex hormone to DHT the hormone mainly responsible for hair follicle miniaturization. When taken orally, finasteride targets the enzyme before the development of DHT occurs. This is in contrast to Rogaine, which just makes it possible for hair follicles to survive in the presence of DHT.

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Finasteride belongs to a group of medications known as 5 alpha-reductase inhibitors. DHT plays a major role in inherited male pattern baldness androgenic alopecia, and by preventing its production finasteride can stimulate hair growth in many men with mild-to-moderate inherited male pattern baldness. The medication usually starts to work within 3 months of beginning treatment. The effectiveness of the medication varies — for most men, it prevents further hair loss and promotes some growth of new hair. In general, however, it will not be possible to grow back all the hair that has been lost.

An example is sodium etidronate. Side effects of bisphosphonates are bone pain and gastrointestinal disturbances. Osteoporosis, literally meaning porous bone, involves a loss of total bone propecia generic costco and a change in the microstructure of bone. This is usually an age-related process that is accelerated in post-menopausal women due to oestrogen deficiency. Oestrogen normally plays a role in the inhibition of bone digestion and this protection is lost after the menopause.

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Many advances in treatment and understanding of the molecular biology of cancer have been made since the mid- curable and there have also been improvements in treatment of ongoing disease and in palliative care. The three main approaches to treatment are surgery, radiotherapy and chemotherapy. The way in which they are combined depends on the type of cancer and its stage at diagnosis. Only a few cancers are treated with chemotherapy alone. New approaches to treatment now include gene therapy, immunotherapy, stimulation of bone marrow, induction of differentiation in cancer cells and inhibition of angiogenesis in addition to the more standard chemotherapy. This chapter will concentrate on the drugs used in cancer chemotherapy with consideration of some of the other forms of therapy.


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