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Acknowledgements I would like to thank friends and colleagues who encouraged and supported me in the writing of this book from its early inception through to final completion. I especially want to thank Leah Greene for her technical expertise and unfailing assistance with computer applications. I am grateful to Alison Barlow and Peter Bowden for their helpful ideas with matters relating to podiatry and Louise Stuart, MBE for an insight into supplementary prescribing; to Jan Dodgeon for help with topics relevant to radiography and Chris Frames and Chris ONeal for their help with devising physiotherapy case studies. Special thanks are due to those who contributed to Chapter Peter Hogg and his co-authors, and Anthony Waddington (Podiatric Surgeon). Without their experience in practice this book would have had far less relevance to the health care professionals for whom it was written.

Adverse reactions to iodine contrast agents are rare, especially with the newer non-ionic dimers of low osmolality. Adverse reactions range from mild effects, such as nausea and vomiting, to moderate effects, such as erythema and chest pain. Severe adverse reactions, for example bronchospasm and anaphylactic shock, always need emergency treatment. Nephrotoxicity is a risk with frequent administration of contrast agents. Patients with conditions predisposing to nephrotoxicity and therefore at high risk should be examined with another method of imaging if possible. Other adverse reactions can be due to the contrast agent binding to body proteins, particularly enzymes.

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