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Drug therapy aims to prevent cell division or cause cell death in the tumour without damaging normal healthy cells. Cancer cells are similar to normal cells, so this is often impossible and explains many of the side effects of chemotherapy.
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Rarely, Parkinsonism can also follow head injuries, cerebral tumours and cerebral ischaemia. At post-mortem, brains of patients with Parkinsons disease are found to contain Lewy bodies.
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In the immunocompromized, lung infections are common because fungi produce spores that can be inhaled, but systemic infection of other internal organs is possible including infection of the blood, heart, kidneys and brain. The cells of fungi have a nucleus, the usual cellular contents, a cell membrane and a cell wall. The fungal cell membrane contains a sterol called ergosterolwhich keeps the membrane stable. In human cell membranes, the sterol is cholesterol. This difference in cell membrane structure allows some selective toxicity of antifungal drugs and most antifungal drugs work by interfering with ergosterol production.
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It is equally important to be able to judge whether a change in a patients condition is caused by drug therapy, or a change in the disease process. Medication can lead to symptoms such as dizziness, fatigue, dry mouth, constipation and patients may or may not associate new symptoms with drug use.
13.07.2017
Ulrich
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It has severe side effects; in particular bone marrow depression, and precipitation of myasthenia gravis and myositis.
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Sebastian
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These are of doubtful therapeutic value, yet bring relief to many patients particularly those with COPD. They can reduce mucus viscosity and ease expectoration.
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Ruth
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Because of this, they are less toxic and produce fewer side effects. However, they contain fewer radio-opaque iodine atoms and therefore are less effective as contrast agents.
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Therese
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Metabolic rickets and osteomalacia result from abnormality in synthesis of or response to calcitriol, the active form of vitamin D.
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Stefan
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