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Also in labour. This practice was widely condemned by the clergy as the work of the devil until Today, either inhalation or intravenous anaesthetics or a combination of the two is used to produce general anaesthesia. Chemically, general anaesthetics are a diverse group of drugs; they are all small lipid soluble molecules, but their mechanism of action is unknown. However, there are two main theories to explain the mechanism of action of general anaesthetics. These are the lipid theory and the protein theory.

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What should you tell her. You should be able to answer these review questions using the information provided in this chapter. You may need to refer to a physiology book for physiology of the autonomic nervous system. The endocrine system includes the endocrine glands and the hormones that they produce.

Alzheimers disease is characterized by atrophy of the cerebral cortex, with loss of neurons particularly in the hippocampus and forebrain. Pathological features of Alzheimers disease are extracellular plaques of β-amyloid protein and neurofibrillary tangles. β-amyloid plaques are found particularly in the hippocampus and association areas of the cerebral cortex. Similar plaques are seen in unaffected individuals, but there are many more in patients with Alzheimers disease.

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Reliable sources of information are the British National Formulary, the British Pharmacopoeia and summaries of product characteristics supplied by medicines manufacturers. Official bodies concerned with the use, quality and safety of medicines are the Commission on Human Medicines, the Medicines and Healthcare Products Regulatory Agency and the National Institute for Health and Clinical Excellence. Patient compliance is important for successful drug therapy. Compliance in this context is defined as the extent to which the patient follows the clinical prescription. Non-compliance and reasons why patients do not always take drugs as prescribed should be appreciated.

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