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Mean doses ranged from Vitamin K 1 is the only effective antidote for long-term management, but it takes several hours to reverse anticoagulation. Intravenous vitamin K 1 has been reported to cause an anaphylactoid reaction but is the preferred route of administration for serious or life-threatening hemorrhage. Vitamin K 1 is used in the management of poisoning and overdose, in the prevention of toxic effects, and in metabolic disorders in which toxic substances accrue. Activated charcoal is the emergency treatment used for poisoning caused by drugs and chemicals.
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