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Those within the agency that blow the whistle on their superiors quickly find themselves demoted and penalized. Undoubtedly the stories of corruption that do emerge are only the tip of the iceberg concerning all of the dirty dealings that happen behind closed doors.

  • Sulphonamides interact with warfarin by enhancing the actions of these drugs.
  • In this situation, the patient shows a response, which can be described under one of the classical definitions of allergic response (that is, type see below).
  • To a certain extent the usefulness of non-medical prescribing depends on the way in which individuals in community podiatry and podiatry in general work.
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The liver, salivary glands, sweat glands and glands of the reproductive organs also produce abnormal secretions. Respiratory symptoms are obstruction of bronchioles with viscous mucus and recurrent infection.

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The persons most likely to be best informed of these changes are pharmacy staff. Controlled drugs are further classified according to the degree of danger that misuse of them presents and for determining penalties for offences under the Act.

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Leukotriene receptor antagonists are a relatively new class of drugs that directly bind to leukotriene receptors in the lung preventing the inflammatory actions of leukotrienes particularly in the late phase of asthma. They are used in cases of asthma where there is a poor response to bronchodilators alone. Current examples are montelukast and zafirlukast, both of which are given orally, either alone or in combination with corticosteroids. They are not recommended for use in chronic bronchitis. Side effects of leukotriene receptor antagonists are gastrointestinal disturbances and headache. Corticosteroids are anti-inflammatory drugs that can be used in asthma to reduce airway hyper-responsiveness and to decrease bronchial oedema and mucus secretion.

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In some circumstances, it may be advantageous to administer a drug rectally, for example if a patient is unconscious or vomiting, or uncooperative in some way, but generally, it is considered an unpleasant method. Many of the general factors considered above that affect absorption from the gastrointestinal tract apply equally to this route of administration. Sublingual administration of a drug allows the drug to go directly into the systemic circulation without first passing through the liver. This route can provide a rapid means of absorption of a drug. It is a route commonly used, for example, to treat attacks of angina with glyceryl trinitrate.


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The pituitary gland plays a very important role in the overall control of the endocrine system.

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That year the law was changed to enable district nurses, midwives and health visitors to prescribe from a limited formulary of dressings, appliances and some medicines.

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