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Drug: Escitalopram Escitalopram, 10mg to 20mg daily. Study participation will last up to two years. Listing a study does not mean it has been evaluated by the U. Federal Government. We report the percentage of subjects at each assessment point adjudged to have independent functioning. Actual Study Completion Date . Phase 4. Participants remained on the same antidepressant medication and dosage throughout the 2 year maintenance phase of the study.

We plan to recruit patients aged 65 and above in current episodes of major depression. R01MH U. Memory Function Elderly Late-Life. Arms and Interventions. Arch Gen Psychiatry. National Institutes of Health U. Department of Health and Human Services. Depression Dementia. For subjects failing to respond to escitalopram during the initial open phase of acute treatment, we allowed the use of duloxetine to bring about remission and establish eligibility for randomized assignment to maintenance treatment with augmentation placebo.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. J Clin Psychiatry. Psychiatry Res. Epub Oct Pilot study of augmentation with aripiprazole for incomplete response in late-life depression: getting to remission. Please refer to this study by its ClinicalTrials. Study Start Date .

Detailed Description. For subjects failing to respond to escitalopram during the initial open phase of acute treatment, we allowed the use of venlafaxine or duloxetine to bring about remission and establish eligibility for randomized assignment to maintenance treatment with augmentation placebo. J Psychiatr Res. Epub Nov Resting state functional connectivity and treatment response in late-life depression.

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