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For the majority of drugs that have a low TR dose adjustment is best made in relation to metabolic rate, which can be estimated from body surface area.
18.10.2019
Lukas
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The importance of the drug therapy can be explained and what might happen if the patient did not comply. Aids to help compliance can be suggested, for example packaging of daily doses can be arranged with pharmacists, special containers can be obtained, the help of relatives can be sought, suitable time of day for administration can be chosen and provision of written information can all help.
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This drug prolongs the refractory period in cardiac muscle without affecting the rate of depolarization.
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Ethosuximide is effective in absence seizures, but not other types of epilepsy. It may even precipitate tonicclonic seizures in susceptible patients.
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