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- Levofloxacin is a fluoroquinolone antibiotic and the optical S- - isomer of racemic ofloxacin.
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Plasma protein binding therefore reduces active drug concentration and ultimate response to the drug. Drugs can compete for the same protein binding sites and this is a form of drug interaction. A well-known and important example is that of warfarin and aspirin. Warfarin is an anticoagulant, which binds extensively to plasma proteins, and this is taken into account when dosages are worked out. Aspirin taken with warfarin competes for the same protein binding sites, which means that they each displace the other and the amount of free drug in the plasma is increased for both drugs.
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In this way, the adrenal glands are activated in response to a threatening situation.
19.02.2017
Heinrich
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Prandial glucose regulators are relatively new oral hypoglycaemics. Examples are nateglinide and repaglinide.
12.01.2016
Veronika
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Concurrent use of allopurinol can reduce the production of uric acid.
13.01.2017
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Calcitonin is the preferred treatment in severe Pagets disease. Side effects of calcitonin are nausea, vomiting and diarrhoea together with flushing, paraesthesia and a peculiar taste in the mouth.
30.11.2017
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There is also elevation of mood, although this may be due to alleviation of distressing symptoms.
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