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The supplementary prescriber must ensure that the supplementary prescribing qualification is recorded on the HPC professional register and have access to continuing professional development thereafter. In the course of prescribing, the supplementary prescriber must enter into a prescribing partnership and agree the CMP with the independent prescriber. They must also arrange for access to prescribing pads and a budget to meet the costs of prescriptions and any other costs. Individuals selected and trained to be supplementary prescribers must have the opportunity to prescribe in partnership with an independent prescriber on completion of training.
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Apoptosis is genetically programmed cell destruction that removes old, redundant and abnormal cells. This guards against mutations surviving and cells becoming malignant. Many cytotoxic anti-cancer drugs damage DNA and initiate apoptosis.
This is because it is now known that joint damage occurs within the first onset of symptoms. In use DMARDs reduce the symptoms and signs of inflammatory joint disease and also improve systemic effects such as vasculitis. In addition, serum markers of disease progression are reduced. For many of these drugs the mode of action is not fully understood, but they all interfere with the activity of cells of the immune system in one way or another. Gold salts accumulate in phagocytic cells thereby reducing their activity and inhibit the migration of lymphocytes into inflamed tissue.
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