Monotherapy in adults, adolescents and children over 6 years of age with partial seizures with or without secondary generalised seizures, and primary generalised tonic-clonic seizures. Adjunctive therapy in children aged 2 years and above, adolescents and adults with partial onset seizures with or without secondary generalization or primary generalized tonic-clonic seizures and for the treatment of seizures associated with Lennox-Gastaut syndrome. Topiramate is indicated in adults for the prophylaxis of migraine headache after careful evaluation of possible alternative treatment options. Topiramate is not intended for acute treatment. It is not necessary to monitor topiramate plasma concentrations to optimize therapy with Topamax. On rare occasions, the addition of topiramate to phenytoin may require an adjustment of the dose of phenytoin to achieve optimal clinical outcome.

Topamax topiramate is a drug approved to treat seizures in adults and children and to reduce the frequency of migraine headaches in people 12 years of age and older. For the treatment of seizures, Topamax may be used alone or in combination with other medications. Topamax is a prescription medication known as an anticonvulsant. The U. As Topamax was used more widely in the s, people began to report various side effects.

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Orphan designation for Captisol-enabled topiramate injection for the treatment of partial onset or primary generalized tonic-clonic seizures in hospitalized patients with epilepsy or those being treated in an emergency care setting who are unable to take oral topiramate. Increased risk for bleeding; in patients with serious bleeding events, conditions that increased the risk for bleeding were present. Body as a whole-general disorders: Oligohydrosis and hyperthermia, hyperammonemia, hyperammonemic encephalopathy, hypothermia with concomitant valproic acid. Gastrointestinal system disorders: Hepatic failure including fatalities, hepatitis, pancreatitis. Vision disorders: Acute myopia, secondary angle closure glaucoma, maculopathy, acute myopia, secondary angle closure glaucoma. Monitor closely for decreased sweating and increased body temperature; oligohydrosis reported with use; monitor during strenuous exercise. Coadministration with valproic acid increases risk of hyperammonemia with or without encephalopathy. Risk of hyperchloremic, non-anion gap, metabolic acidosis; especially if concomitant renal disease, severe respiratory disorder, status epilepticus, diarrhea, surgery, ketogenic diet, or drugs predisposing to acidosis; if metabolic acidosis develops and persists, consideration should be given to reducing dose or discontinuing therapy using dose tapering ; if decision is made to continue patients on therapy in face of persistent acidosis, alkali treatment should be considered.

Patient acceptability may be enhanced by lack of weight gain, lack of major contraindications, and positive effects on quality of life. Migraine is a chronic neurological disorder characterized by recurrent attacks of headache and other symptoms which may last up to 3 days. The pain is moderate to severe, and is associated with other symptoms, such as phonophobia, photophobia, nausea, and vomiting. Prodromes like somnolence and mood changes may also be present. In some patients the headache phase is preceded by aura, a complex of focal neurological symptoms, which may include visual disturbances, numbness, paresthesia, and speech difficulties Headache Classification Subcommittee of the International Headache Society ; Lipton et al The prevalence rate of migraine with or without aura in the US in was

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I decadron kenalog 80 mg found out that I am pregnant. I am aware of the initial findings that are included in the medication insert but that is all. Hello ladies I know everyone'e fears and concerns all to well. I am 7 weeks pregnant with my third child second one while on Topamax. Under a doctors advice of course is ok.

He recovered rapidly despite an initial TPM concentration of To our knowledge, this is the first report of a patient who survived such a high TPM concentration. The case indicates that nonconvulsive status epilepticus could be a manifestation of TPM intoxication. It was suspected that he had had a generalized tonic—clonic seizure GTCS, and he was admitted to the hospital. On admission he was drowsy and disoriented, initially responded inappropriately, and then became unresponsive. The patient has a history of idiopathic generalized epilepsy IGE with absence seizures since childhood.

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UK Edition. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have any further questions, ask your doctor or pharmacist. This medicine has been prescribed for you only. Do not pass it on to others.

What Is Topamax? Topamax topiramate is an anticonvulsant prescribed for preventing epileptic seizures and migraine headaches. Topamax is available as a generic drug. Drug interactions include acetazolamide Diamox, methazolamide Neptazane, dichlorphenamide Daranide, carbamazepine Tegretol and phenytoin Dilantin and oral contraceptives. There are no adequate studies of Topamax in pregnant women and it is not known if Topamax is secreted in human breast 200 mg topamax.

Warning: The primary use of Topiramate, and the only use for which it has regulatory approval, is to treat seizures. Medical researchers currently do not know how Topiramate works. The FDA gave final approval for the drug on December 24, As stated above, the only approved use to date is the treatment of convulsions. There are two things that set Topiramate apart from other drugs in this class.

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