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Antihistamine group.
Phenytoin belongs to the group of medications known as anti-epileptics. Myths: Pneumococcal disease.
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Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants. Clinicians are advised to initiate therapeutic drug monitoring in patients who require phenytoin since even small deviations from the recommended therapeutic range can lead to suboptimal treatment, or adverse effects. A governmentally-recognized ID which uniquely identifies the product within its regulatory market. Phenytoin is an anticonvulsant with a narrow therapeutic index. It is worth nothing that although phenytoin is highly protein bound, only the fraction unbound is able to exert a pharmacological effect. Phenytoin is often described as a non-specific sodium channel blocker and targets almost all voltage-gated sodium channel subtypes. Comprehensive structured data on known drug adverse effects with statistical prevalence. Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used.
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Phenytoin is used to control certain type of seizures, and to treat and prevent seizures that may begin during or after surgery to the 2 mg dilantin or nervous system. Phenytoin comes as an extended-release long-acting capsule, a chewable tablet, and a suspension liquid to take by mouth. The chewable tablet and suspension are usually taken two or three times a day. The extended-release capsules are usually taken one to four times a day. Take phenytoin at around the same time s every day. Take phenytoin exactly as directed.
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Ensure ECG, blood pressure and respiratory function are monitored throughout the duration of the infusion. Oral or nasogastric administration should be used, whenever possible. Only use intravenous administration when these options are not feasible and where cardiac monitoring is available. Table 3 below is for maintenance dose adjustment only. For 'top-up' doses in urgent situations see Table 2 above.
Common side effects include nausea, stomach pain, loss of appetite, poor coordination, increased hair growth, and enlargement of the gums. Phenytoin was first made in by the German chemist Heinrich Biltz and found useful for seizures in Potentially serious side effects include sleepiness, self harm, liver problems, bone marrow suppression, low blood pressure, and toxic epidermal necrolysis. There is evidence that use during pregnancy results in abnormalities in the baby. Its use appears to be safe during breastfeeding. Alcohol may interfere with the medication's effects.
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Your medication may look different. If you have questions, ask your pharmacist. Pronunciation FEN-i-toyn. This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
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Environmental changes or excessive stimulation can cause a reduction in membrane sodium gradient. Phenytoin causes an efflux of sodium from neurons and therefore stabilises the threshold against over-activity in those brain stem centres responsible for the tonic phase of grand mal seizures 9.
- Initially, one gram of Dilantin extended phenytoin sodium capsules, USP is divided into three doses mg, mg, mg and administered at two-hour intervals.
- What is Dilantin?
- The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient.
- Phenytoin belongs to the group of medications known as anti-epileptics.
- All these medications are opioids.
- The most common adverse reactions are nervous system reactions, including nystagmus, ataxia, slurred speech, decreased coordination, somnolence, and mental confusion.
Patients who are hypersensitive to phenytoin, other hydantoins, or any of the excipients. Coadministration of DILANTIN with delavirdine is contraindicated due to potential for loss of virologic response and possible resistance to delavirdine or to the class of non-nucleoside reverse transcriptase inhibitors.
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It works by slowing down impulses in the brain that cause seizures. Dilantin is used to control seizures.
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Parenteral preparations are available if oral therapy cannot be tolerated. Decreased production of erythrocytes can be a cause of anaemia. This can be due to deficiency of vitamin B for formation of erythrocytes. Vitamin B the stomach and is essential for absorption of vitamin B of impaired absorption due to disease of the small intestine. Oral replacement of vitamin B by intramuscular injection of hydroxycobolamin, a form of vitamin B Folic acid deficiency can occur due to pregnancy, malabsorption syndromes or inadequate diet.
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Many well-established antiepileptic drugs (for example phenobarbital and benzodiaze pines) are known to facilitate the opening of GABA chloride ion channels at synapses. However, this is not the complete explanation as, for example phenobarbital is far more effective as an anticonvulsant than other barbiturates with the same enhancing effects on GABA.
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