Displays peripheral selectivity and does not effect serum levels of LH and testosterone. Exhibits potent anticancer activity in vivo. Find out more about compound libraries available from Tocris. The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. Tocris products are intended for laboratory research use only, unless stated otherwise.

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Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a composition of the R -bicalutamide and S -bicalutamide enantionmers. Bicalutamide binds to the androgen receptor. A governmentally-recognized ID which uniquely identifies the product within its regulatory market. Bicalutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Bicalutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors but not for progestogen, estrogen, or glucocorticoid receptors. Consequently, Bicalutamide blocks the action of androgens of adrenal and testicular origin which stimulate the growth of normal and malignant prostatic tissue. Prostate cancer is mostly androgen-dependent and can be treated with surgical or chemical castration.

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What is bicalutamide, and how does it work mechanism of action? Bicalutamide is an oral medication that is used for treating cancer of the order casodex bicalutamide. Androgens an example of which is testosterone are hormones that are produced and released by the adrenal glands. Male traits that also are influenced by androgens include facial and body hair, and small breasts. Anti-androgens prevent the action of androgens by blocking the receptors for androgens on the cells of tissues, for example, the cells of the prostate gland. Bicalutamide is thought to prevent the growth of prostate cancer by blocking the effects of androgens on the cancer cells.

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It is classified as an anti-androgen. For more detail, see How this drug works section below. Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful. You will be checked regularly by your doctor while you are taking bicalutamide, to monitor side effects and check your response to therapy. Periodic blood work to monitor your complete blood count CBC as well as the function of other organs such as your kidneys and liver will also be ordered by your doctor. Growth of prostate cancer may be stimulated by male hormones androgens, primary testosterone circulating in the body.

Casodex bicalutamide, Zeneca Limited is a nonsteroidal competitive inhibitor of androgens at the androgen receptor. The drug was developed to fulfil a number of needs for the treatment of prostate cancer. The specific aim was to demonstrate pharmacological activity, which would translate into clinical efficacy, good tolerability in the context of its use, oral availability, a convenient and forgiving dosing regimen, and clinical acceptability. Although steady-state levels are not reached for 1 month, there is evidence that the androgen receptor blockade achieved with Casodex is equivalent to that of flutamide by the end of the first day. The dose of Casodex was established in a series of dose-ranging studies using the surrogate endpoints of prostatic acid phosphatase PAP and prostate-specific antigen PSA.

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In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Safety and efficacy have not been established.

Casodex bicalutamide is an anti-androgen. It works in the body by preventing the actions of androgens male hormones. Casodex is used together with another hormone to treat prostate cancer. Casodex is used to treat prostate cancer. This medicine should never be taken by a woman or a child.

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