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An outline of normal physiology of the systems is included where appropriate and relevant diseases described briefly. This is not intended to be a physiology book or a pathophysiology book.
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Antimetabolites are analogues or antagonists of normal cell constituents, which block or otherwise alter metabolic pathways in the synthesis of DNA. Cytotoxic antibiotics prevent cell division by direct action on DNA or by inhibition of transcription of DNA to RNA, thus preventing protein synthesis.
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