Washington, D. Report of Foreign Private Issuer. For the month of February Teva Pharmaceutical Industries Limited. Box Address of principal executive offices. If Yes is marked, indicate below the file number assigned to the registrant in connection with Rule 12g 3 -2 b :

Changes in funded brands of antiepileptic medicines can lead to concern from patients or caregivers that the medicine they are receiving is not the same and may not be as effective. Counselling in general practices and pharmacies is imperative to talk through any concerns patients may have about changing brands of medicines and to provide reassurance that although their tablets may look different, they are still receiving the same medicine. This article has been distributed to primary healthcare professionals, and specialist interest groups in New Zealand paediatric, neurology and psychology groups. Lamotrigine is an antiepileptic medicine used in the treatment of patients with focal, generalised or absence seizures. There are currently three funded brands of lamotrigine in 25 mg, 50 mg and mg dispersible tablets. These brands have been available fully funded without restriction for over ten years Table 1.

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Common side effects include sleepiness, headache, vomiting, trouble with coordination, and rash. Lamotrigine was first marketed in the United Kingdom in, and approved for use in the United States in Lamotrigine is considered a first-line drug for primary generalized tonic-clonic seizures includes simple partial, complex partial, and secondarily generalized seizures such as focal-onset tonic-clonic seizures. It is also used as an alternative or adjuvant medication for partial seizures, such as absence seizure, myoclonic seizure, and atonic seizures. Lamotrigine is approved in the US for maintenance treatment of bipolar I disorder and bipolar II disorder. The drug seems ineffective in the treatment of current rapid-cycling, acute mania, or acute depression in bipolar disorder; however, it is effective at prevention of or delaying of manic, depressive, or rapid cycling episodes.

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Common side effects include sleepiness, headache, vomiting, trouble with coordination, and rash. TRPs See here instead.

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Or in a crisis, text NAMI to Or in a crisis.

Lamictal is used alone or in combination with other drugs to treat seizures in adults and children with epilepsy. In addition, Lamictal is commonly prescribed to adults with bipolar disorder manic depression to delay episodes of depression and mania. Mania is defined as frenzied or abnormally excited moods. Lamictal is also prescribed off-label to treat clinical depression and migraine headaches. The FDA first approved Lamictal in as an anti-seizure medication.

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Serious rashes requiring hospitalization including Stevens-Johnson syndrome and discontinuation of treatment have occurred in 0. Almost all life-threatening rashes have occurred within 2- 8 weeks of lamotrigine therapy, but they have also occurred after prolonged treatment; duration cannot be relied on as a means to predict the potential risk heralded by the first appearance of a rash. Although benign rashes also occur with lamotrigine, it is not possible to predict reliably which rashes will prove to be serious or life threatening. Discontinuation of treatment may not prevent a rash from becoming life threatening or permanently disabling or disfiguring. Rare cases of toxic epidermal necrolysis have been reported in worldwide postmarketing experience.

Or in a crisis, text NAMI to All FDA black box warnings are at the end of this fact sheet. Lamotrigine is a mood stabilizer medication that works in the brain. It is approved for the treatment of bipolar disorder also known as manic depression and certain types of seizure disorders. They should be clear about the limits of the research around that medication and if there are any other options.

These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication. Other brands: Subvenite. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Drug Exclusivity Exclusivity is the sole marketing rights granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent.

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