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As an oral drug, capecitabine is preferred to 5-FU by many patients as it can be conveniently taken at home. In first-line metastatic colorectal cancer MCRC, capecitabine results in superior response rates and equivalent progression-free and overall survival compared with i. There is also increasing evidence for replacing i. In anthracycline-pretreated metastatic breast cancer MBC, adding capecitabine to docetaxel improves survival, time to progression TTP and response rates beyond docetaxel. Single-agent capecitabine is also effective in pretreated MBC and is a promising first-line therapy.

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