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Adverse effects of carbamezepine are similar to those seen with phenytoin. They include the relatively mild drowsiness, dizziness and ataxia, to the more severe mental and motor disturbances.
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Chloroquine and hydroxychloroquine are sometimes used to treat systemic and discoid lupus erythematosus, but should not be used for psoriatic arthritis.
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However, there is frequently a secondary reaction often many hours later due to mechanisms other than histamine release. This is known as the late phase reaction and is usually less responsive to treatment than the immediate phase reaction.
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