300 mg dilantin

Adjust the dosage to suit individual requirements up to a maximum of two capsules three times a day.

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Phenytoin works by slowing down impulses in the brain that cause seizures. Phenytoin is used to control seizures. It does not treat all types of seizures, and your doctor will determine if it is the right medicine for you. You should not use phenytoin if you also take delavirdine Rescriptor, or if you are allergic to ethotoin Peganone, fosphenytoin Cerebyx, or mephenytoin Mesantoin. Phenytoin may cause harm to an unborn baby, but having a seizure during pregnancy could harm both the mother and the baby.

Dosage should be individualized to provide maximum benefit. Serum blood level determinations are especially helpful when possible drug interactions are suspected. With recommended dosage, a period of 7 to 10 days may be required to achieve therapeutic blood levels with DILANTIN and changes in dosage increase or decrease should not be carried out at intervals shorter than 7 to 10 days. Patients who have received no previous treatment may be started on one mg extended phenytoin sodium capsule three times daily, and the dose then adjusted to suit individual requirements. For most adults, the satisfactory maintenance dosage will be three to four capsules mg daily. An increase to six capsules daily may be made, if necessary. Phenytoin clearance is decreased slightly in elderly patients.

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Phenytoin injection is contraindicated in patients with sinus bradycardia, sino-atrial block, second or third degree AV block, and Adams-Stokes syndrome because of the effects of the drug on ventricular automaticity. Intravenous phenytoin should not be used in patients with other cardiac conduction abnormalities e. Most cases of cardiac arrest occurred in patients with underlying cardiac disease. Severe cardiovascular reactions have occurred, including bradycardia, heart block, ventricular tachycardia, and ventricular fibrillation, which have resulted in asystole, cardiac arrest, and death in some cases. Although the risk of cardiovascular toxicity is increased with rapid intravenous administration, cardiac events have also been reported at or below the recommended infusion rates. Careful cardiac and respiratory monitoring is required during and after intravenous phenytoin administration. A reduction in the rate of administration or discontinuation of the drug may be necessary if cardiac reactions occur.

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The most common adverse reactions are nervous system reactions, including 300 mg dilantin, ataxia, slurred speech, decreased coordination, somnolence, and mental confusion. Multiple drug interactions because of extensive plasma protein binding, saturable metabolism and potent induction of hepatic enzymes. Adjust the dosage to suit individual requirements up to a maximum of two capsules three times a day. In patients with renal or hepatic disease, or in those with hypoalbuminemia, the monitoring of unbound phenytoin concentrations may be more relevant. Most of the reports of cardiac arrest occurred in patients with underlying cardiac disease.

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Case report. A year-old woman was admitted to our hospital with encephalopathy and clinical signs of cerebellar dysfunction. She had recently received an overdose of phenytoin. The patient's neurological condition improved rapidly after withdrawal of phenytoin. Cerebellar atrophy due to acute phenytoin intoxication is very unusual but few cases have been reported. The present clinical and radiological findings suggest that short-term phenytoin overdose alone may cause cerebellar atrophy.

300 mg dilantin


Phenytoin is used to control certain type of seizures, and to treat and prevent seizures that may begin during or after surgery to the brain or nervous system. Phenytoin comes as an extended-release long-acting capsule, a chewable tablet, and a suspension liquid to take by mouth. The chewable tablet and suspension are usually taken two or three times a day. The extended-release capsules are usually taken one to four times a day. Take phenytoin at around the same time s every day. Take phenytoin exactly as directed.

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Initially: mg 3 times daily. Increase weekly if needed; max mg 3 times daily. Once-a-day dosing only with ext-rel caps for patients controlled on mg daily. Increase weekly if needed. Suicidal tendencies monitor.

Almost all typical TN sufferers experience significant pain relief with carbamazepine. The starting daily dose is low, one to two pills a day, which is gradually increased until the pain is completely alleviated or side effects occur. Good relief of pain may be achieved at low doses, but the usual effective dose ranges from to mg divided in three or four doses per day. Even higher doses may be required during severe attacks of pain. Once relief of the pain has been achieved, the same dose is usually continued for at least two weeks before trying to reduce to a minimal dosage that provides pain relief. If side effects are severe, the daily dose of carbamazepine may be decreased for 1 to 3 days, before trying to increase the daily dose again.

300 mg dilantin


Phenytoin belongs to the group of medications known as anti-epileptics. It works on the brain to reduce the number and severity of seizures. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do.


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