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Women aged less than 30 years old were excluded from primary prevention trials so the efficacy and safety of tamoxifen treatment in these younger women is unknown. Adults: The recommended daily dose of tamoxifen is normally 20mg. Elderly people: Similar dosing regimens of tamoxifen have been used in older people with breast cancer and in some of these patients it has been used as sole therapy. The recommended dose is 20 mg daily for 5 years for those women at moderate or high risk. Validated algorithms are available that calculate breast cancer risk based on features such as age, family history, genetic factors, reproductive factors and history of breast disease.

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