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Rectal administration avoids drug inactivation by stomach acid and digestive enzymes and about circulation. In some circumstances, it may be advantageous to administer a drug rectally, for example if a patient is unconscious or vomiting, or uncooperative in some way, but generally, it is considered an unpleasant method.
Antiepileptic drugs are summarized. Alzheimers disease is the term given to dementia that cannot be attributed to an obvious cause, for example brain trauma, a stroke or alcohol abuse. Alzheimers disease is a gradual and irreversible decline in intellectual ability that usually appears after the age of progressive loss of cognitive function, usually beginning with loss of short-term memory followed by loss of other functions such as ability to calculate and ability to use everyday objects. Alzheimers disease is characterized by atrophy of the cerebral cortex, with loss of neurons particularly in the hippocampus and forebrain. Pathological features of Alzheimers disease are extracellular plaques of β-amyloid protein and neurofibrillary tangles.
Chloroquine and hydroxychloroquine are sometimes used to treat systemic and discoid lupus erythematosus, but should not be used for psoriatic arthritis. Because of the risk of retinopathy, long-term therapy should be reserved for cases in which all other DMARDs have failed. Immunosuppressants, such as azathioprine, ciclosporin and methotrexate, can be used to treat severe inflammatory disease. Their use depends on their ability to inhibit the activity and proliferation of lymphocytes and other leukocytes and because of this they are very toxic to the bone marrow. Other adverse effects are nausea, leukopenia, blurred vision, rashes and hair loss. Cytokines are chemicals released by damaged cells and cells involved in inflammation and repair.
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This requires the action of enzymes. New nucleotides pair C cytosine G guanine T thymine A adenine base sugar base phosphate Figure with the existing bases of each strand: adenine nucleotides pair with thymine; guanine nucleotides pair with cytosine.
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The expectation was that extending prescribing would optimize the use of resources, enhance professional relationships and improve patient access to care. The report defined mechanisms for what were to become supplementary prescribing and independent prescribing, and recommended that other groups of professionals should be able to legally prescribe.
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